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Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.
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Titel
  • Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.
Anmärkning: Innehållsbeskrivning, sammanfattning
  • All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide<0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were no gender differences in type 1 in any age group, small ones in pediatric subgroups. In type 2 men predominated in ages above 40 years. Incidences of type 1 diabetes in both children and adults were very high and as high above age 50 years as in children. Incidence of type 2 was the highest reported from Sweden, to which new diagnostic criteria, a high degree of case-finding, and many elders, may have contributed, but results may also reflect a true increase in incidence of both types of diabetes.
Ämne
Medarbetare
  • Petersson, C Författare/medförfattare
  • Jonzon, K Författare/medförfattare
  • Fornander, J Författare/medförfattare
  • Ossiansson, B Författare/medförfattare
  • Törn, Carina Författare/medförfattare
  • Edvardsson, S Författare/medförfattare
  • Landin-Olsson, Mona Författare/medförfattare
Institutionsnamn
Värdpublikation
  • Diabetes research and clinical practice ISSN 1872-8227 :2008 Sep 17. :2008 Sep 17.
Elektronisk adress och åtkomst (URI)
  • Fulltext, begränsad tillgänglighet
  • Fulltext, begränsad tillgänglighet
  • Till lärosätets (lu) databas
  • G:\Gemensamt\FoU Kronoberg\Text hemsidan - Dorthe\Artiklar\2008\maria th Incidence of type 1 and 2 diabetes 2008.pdf Fulltext
Antal i kö:
  • 0 (0)
 
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*24510$aIncidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.
*5203 $8eng$aAll newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide<0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were no gender differences in type 1 in any age group, small ones in pediatric subgroups. In type 2 men predominated in ages above 40 years. Incidences of type 1 diabetes in both children and adults were very high and as high above age 50 years as in children. Incidence of type 2 was the highest reported from Sweden, to which new diagnostic criteria, a high degree of case-finding, and many elders, may have contributed, but results may also reflect a true increase in incidence of both types of diabetes.
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